| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm | Welcome: Bill Goldman (Washington University) |
| 7:40 pm - 9:40 pm | EVOLUTION AND GENETIC DIVERSITY OF BACTERIAL PATHOGENS |
| Discussion Leader: John Mekalanos (Harvard Medical School) |
| 7:40 pm - 8:20 pm | Nina Salama (Fred Hutchinson Cancer Research Center)
"A Global View of Helicobacter pylori Strain Diversity and Virulence" |
| 8:20 pm - 9:00 pm | Brendan Wren (London Sch. Hygiene & Tropical Med.)
"The Yersinia Genome Recipe: Add DNA, Stir and Reduce" |
| 9:00 pm - 9:40 pm | Pascale Cossart (Institut Pasteur)
"Comparative Genomics of Listeria Species: New Insights in Virulence" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am - 9:00 am | Photo |
| 9:15 am - 12:30 pm | BACTERIAL CELL BIOLOGY AND PATHOGENESIS |
| Discussion Leader: Stephen Lory (Harvard Medical School) |
| 9:15 am - 9:55 am | Ronald Taylor (Dartmouth Medical School)
"Mechanisms of TCP Biogenesis and Function" |
| 9:55 am - 10:20 am | Karl Klose (University of Texas - San Antonio)
"Control of Polysaccharide Synthesis by Motility in Vibrio cholerae"
|
| 10:20 am - 10:45 am | Seema Mattoo (University of California - Los Angeles)
"Regulation of Type III Secretion in Bordetella"
|
| 10:45 am | Coffee Break |
| 11:10 am - 11:50 am | Marcia Goldberg (Massachusetts General Hospital/Harvard Medical School)
"Polar Targeting of Shigella IcsA among Enterobacteriacae" |
| 11:50 am - 12:30 pm | Maria Sandkvist (American Red Cross)
"Polar Secretion via the Type II Apparatus in Vibrio cholerae" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I
|
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | HOST CELL SIGNALING BY BACTERIA |
| Discussion Leader: Dan Portnoy (University of California - Berkeley) |
| 7:30 pm - 8:10 pm | Brad Cookson (University of Washington)
"Pyroptosis: Pro-Inflammatory Host Cell Death Induced by Salmonella" |
| 8:10 pm - 8:50 pm | Dana Philpott (Institut Pasteur)
"Intracellular Sensing of Endotoxin" |
| 8:50 pm - 9:30 pm | Michael Donnenberg (University of Maryland)
"EPEC: What's a Translocator and What's and Effector?" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TOXINS AND EFFECTORS: TRANSLOCATION |
| Discussion Leader: Sam Miller (University of Washington) |
| 9:00 am - 9:40 am | Michael Caparon (Washington University)
"Cytolysin-Mediated Translocation in Streptococcus" |
| 9:40 am - 10:05 am | John Leong (University of Massachusetts Medical School)
"Actin pedestal formation by EPEC"
|
| 10:05 am - 10:45 am | Drusilla Burns (Food and Drug Administration)
"Assembly of Pertussis Toxin and its Secretion via a Type IV Transporter" |
| 10:45 am | Coffee Break |
| 11:10 am - 11:50 am | James Bliska (State University of New York - Stony Brook)
"Modulation of Host Signaling Pathways by Yersinia Yop Proteins" |
| 11:50 am - 12:30 pm | Mary Beth Mudgett (Stanford University)
"Delivery of Type III Effectors Specifying Plant Disease and Innate Immunity" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I (continued) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TRAFFICKING WITHIN HOST CELLS |
| Discussion Leader: Pascale Cossart (Institut Pasteur) |
| 7:30 pm - 8:10 pm | Ted Hackstadt (NIAID Rocky Mountain Laboratories)
"Biogenesis of the Chlamydial Inclusion" |
| 8:10 pm - 8:50 pm | Chihiro Sasakawa (University of Tokyo)
"Shigella Invasion and Spreading" |
| 8:50 pm - 9:30 pm | David Russell (Cornell University)
"Modulation of Host Function by Mycobacterium" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | INTRACELLULAR PATHOGENESIS |
| Discussion Leader: David Russell (Cornell University) |
| 9:00 am - 9:40 am | Dan Portnoy (University of California - Berkeley)
"The Fail-Safe Mechanisms of Listeriolysin O" |
| 9:40 am - 10:20 am | David Holden (Imperial College of Science, Technology and Medicine)
"Intracellular Activities of Salmonella" |
| 10:20 am - 10:45 am | Corrie Detweiler (Stanford University)
"Beyond the Peyer's Patch -- Salmonella and Late Stages of Infection" |
| 10:45 am | Coffee Break |
| 11:10 am - 11:50 am | Philippe Gros (McGill University)
"Nramp Proteins, Resistance to Infection and Divalent Cations Transport" |
| 11:50 am - 12:30 pm | Joel Swanson (University of Michigan Medical School)
"Calcium and pH in and around Macrophage Phagosomes" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | EXTRACELLULAR PATHOGENESIS |
| Discussion Leader: Alison O'Brien (Uniformed Services U. of the Health Sciences) |
| 7:30 pm - 8:10 pm | Jeffrey Weiser (University of Pennsylvania)
"Phosphorylcholine on Pathogens of the Respiratory Tract" |
| 8:10 pm - 8:50 pm | Peter Dube (Washington University)
"Yersinia Infection and the Role of Inflammatory Cytokines" |
| 8:50 pm - 9:30 pm | Gadi Frankel (Imperial College)
"EPEC/EHEC Intimin-Mediated Tissue Tropism" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | BACTERIAL AND HOST GENE REGULATION DURING INFECTION |
| Discussion Leader: Virginia Miller (Washington University) |
| 9:00 am - 9:40 am | Victor DiRita (University of Michigan)
"Capsule Regulation in Invasive Streptococcal Skin Infection" |
| 9:40 am - 10:05 am | Rod Welch (University of Wisconsin)
"Is E. coli Uropathogenesis a Matter of Having the Right Serine?"
|
| 10:05 am - 10:45 am | Lora Hooper (Washington University)
"Exploring How Normal Gut Bacteria Influence Host Physiology and Development" |
| 10:45 am | Coffee Break |
| 11:10 am - 11:50 am | Peggy Cotter (University of California - Santa Barbara)
"How and Why Bordetella Alter their Phenotypic Profile during the Infectious Cycle" |
| 11:50 am - 12:30 pm | Peter Greenberg (University of Iowa)
"Quorum Sensing, Biofilms and Virulence in Pseudomonas aeruginosa" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II (continued) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TOXINS AND EFFECTORS: STRUCTURE & FUNCTION |
| Discussion Leader: Erik Hewlett (University of Virginia) |
| 7:30 pm - 8:10 pm | Joe Barbieri (Medical College of Wisconsin)
"Structure/function properties of Pseudomonas ExoS" |
| 8:10 pm - 8:50 pm | Carleen Collins (University of Washington)
"Pathogenesis of Staphylococcal Scalded Skin Syndrome" |
| 8:50 pm - 9:30 pm | John Collier (Harvard University)
"Anthrax Toxin: Structure, Activity, and New Inhibitors" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
