| SUNDAY, July 18 |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 4:00 pm - 6:00 pm | Wine and cheese reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GENOMICS AND GLOBAL GENE REGULATION |
| 7:30 pm - 7:45 pm | Discussion Leader: Jeffrey F. Miller (UCLA School of Medicine) |
| 7:45 pm - 8:20 pm | John Mekalanos (Harvard Medical School)
"V. cholerae genomics" |
| 8:20 pm - 8:55 pm | Joseph Heitman (Duke University Medical Center)
"Evolution of virulence in Cryptococcus" |
| 8:55 pm - 9:30 pm | Agnes Fouet (Pasteur Institute, Paris)
"B. anthracis global gene regulation" |
| MONDAY, July 19 |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | TOXINS |
| 9:00 am - 9:15 am | Discussion Leader: R. John Collier (Harvard Medical School) |
| 9:15 am - 9:55 am | John A.T. Young (Salk Institute for Biologic Studies, San Diego)
"Anthrax toxin and its receptors" |
| 9:55 am - 10:10 am | Borden Lacy (Harvard Medical School)
"The crystal structure of anthrax toxin protective antigen bound to its receptor, cmg2" |
| 10:10 am - 10:50 am | John R. Murphy (Boston University School of Medicine)
"Translocation of diphtheria toxin" |
| 10:50 am - 11:15 am | Coffee Break |
| 11:15 am - 11:55 am | Rodney K. Tweten (University of Oklahoma Health Sciences Center)
"The molecular basis of pH-dependent pore formation by Listeriolysin O" |
| 11:55 am - 12:30 pm | Pam Small (University of Tennessee, Knoxville)
"Macrolide-mediated virulence in Mycobacterial pathogens" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | NEW APPROACHES TO THE STUDY OF MICROBIAL PATHOGENESIS |
| 7:30 pm - 7:45 pm | Discussion Leader: Stephen Lory (Harvard Medical School) |
| 7:45 pm - 8:20 pm | Eric Rubin (Harvard School of Public Health)
"Mycobacterial genetics - talkin' TraSH" |
| 8:20 pm - 8:55 pm | James Sacchettini (Texas A&M University)
"Structural genomics" |
| 8:55 pm - 9:30 pm | Carolyn Bertozzi (University of California, Berkeley)
"Sulfation pathways in Mycobacterium tuberculosis" |
| TUESDAY, July 20 |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | VACUOLAR PATHOGENS |
| 9:00 am - 9:15 am | Discussion Leader: Ralph Isberg (Tufts University) |
| 9:15 am - 9:55 am | Michele Swanson (University of Michigan, Ann Arbor)
"Autophagy as a macrophage response to infection" |
| 9:55 am - 10:35 am | Jean-Pierre Gorvel (Centre d'Immunologie de Marseille-Luminy)
"Brucella, a hidden bug in the ER" |
| 10:35 am - 11:05 am | Coffee Break |
| 11:05 am - 11:25 am | Joanne Engel (University of California, San Francisco)
"Use of RNAi in Drosophiila cells to dissect pathways of Pseudomonas
entry and Chlamydial development" |
| 11:25 am - 11:45 am | Raphael Valdivia (Duke University Medical Center)
"Functional genomics of the Chlamydia inclusion" |
| 11:45 am - 12:25 pm | Samuel I. Miller (University of Washington, Seattle)
"Salmonella survival and replication within macrophage phagosomes" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | COLONIZATION AND INTERNALIZATION |
| 7:30 pm - 7:45 pm | Discussion Leader: Drusilla L. Burns (FDA) |
| 7:45 pm - 8:20 pm | Michael J. Koomey (Biotechnology Centre, Oslo, Norway)
"Unique post-translational modifications of N. gonorrhoeae Type IV pili: sugar and spice with some things twice" |
| 8:20 pm - 8:55 pm | Pascale Cossart (Pasteur Institute, Paris)
"Bacterial invasion: the Listeria paradigm" |
| 8:55 pm - 9:30 pm | Jorge Galan (Yale University School of Medicine)
"Modulation of cellular functions by Salmonella" |
| WEDNESDAY, July 21 |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | BACTERIAL MANIPULATION OF HOST INNATE IMMUNITY |
| 9:00 am - 9:15 am | Discussion Leader: Staffan Normark (Karolinska Institute, Stockholm) |
| 9:15 am - 9:50 am | Brian Staskawicz (University of California, Berkeley)
"The molecular basis of plant innate immunity in Arabidopsis thaliana" |
| 9:50 am - 10:20 am | Richard Darveau (University of Washington, Seattle)
"Porphyromonas gingivalis Lipopolysaccharide: Lipid A heterogeneity
and modulation of innate host responses" |
| 10:20 am - 10:50 am | Coffee Break |
| 10:50 am - 11:25 am | Jurgen Heesemann (Max von Pettenkofer-Institut fur
Hygiene und Mikrobiologie, Munich)
"V antigen and TLR signaling in Yersinia" |
| 11:25 am - 12:00 pm | Jeffery Cox (University of California, San Francisco)
"M. tuberculosis control of macrophage function" |
| 12:00 pm - 12:30 pm | Lalita Ramakrishnan (University of Washington, Seattle)
"Mycobacterium-host interactions in real time in a transparent Zebrafish
embryo model" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | HOST CYTOSKELETON AND CYTOSOLIC PATHOGENS |
| 7:30 pm - 7:45 pm | Discussion Leader: Marcia Golberg
(Mass General / Harvard School of Medicine) |
| 7:45 pm - 8:20 pm | Eric J. Brown (University of California, San Francisco)
"Mycobacterium marinum - escape and run" |
| 8:20 pm - 8:55 pm | Matt Welch (University of California, Berkeley)
"Role of Arp2/3 complex-mediated actin nucleation in bacterial and viral pathogenesis" |
| 8:55 pm - 9:30 pm | Julie Theriot (Stanford School of Medicine)
"Early events in actin recruitment by Listeria monocytogenes" |
| THURSDAY, July 22 |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am - 9:05 am | Business meeting and election of 2006 chair |
| 9:05 am - 12:30 pm | PERSISTENT INFECTIONS |
| 9:05 am - 9:20 am | Discussion Leader: Stanley Falkow
(Stanford School of Medicine) |
| 9:20 am - 10:00 am | John McKinney (Rockefeller University, New York)
"Hard Target: Persistence Mechanisms in Mycobacterium" |
| 10:00 am - 10:40 am | Jane E. Koehler (University of California, San Francisco)
"Bartonella: a persistent hemophile" |
| 10:40 am - 11:10 am | Coffee Break |
| 11:10 am - 11:50 am | Denise Monack (Stanford School of Medicine)
"Persistent Salmonella infections" |
| 11:50 am - 12:30 pm | Ranier Haas (Max von Pettenkofer Institut, Munich)
"Helicobacter pylori: persistence and T cell modulation" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | INFECTION
AND IMMUNITY |
| Discussion Leader: Eric G. Pamer (Memorial Sloan-Kettering Cancer Center, NY) |
| 7:30 pm - 8:15 pm | Eric G. Pamer
(Memorial Sloan-Kettering Cancer Center, NY)
"Innate and adaptive immune responses to Listeria monocytogenes infection" |
| 8:15 pm - 9:00 pm | Rino Rappuoli (Chiron Vaccines, Siena)
"Reverse vaccinology: a genome-based vaccine development" |
| 9:00 pm - 9:30 pm | Concluding Discussion |
| FRIDAY, July 23 |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
