SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | TOXINS AND PATHOGENICITY (KEYNOTES) |
7:40 pm - 7:50 pm | Discussion Leader: Vic DiRita (University of Michigan) |
7:50 pm - 8:25 pm | Cesare Montecucco (University of Padova)
"Toxin mechanisms and the evolution of toxigenic bacteria" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:15 pm | Daniel A. Portnoy (University of California-Berkeley)
"Intracellular pathogens and innate immunity: A bacteriologist's perspective" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | TOXIN MECHANISMS OF ACTION |
9:00 am - 9:15 am | Discussion Leader: Karla Fullner Satchell (Northwestern University) |
9:15 am - 9:40 am | Kim Orth (UT-Southwestern)
"Black Death, Black Spot, Black Pearl: Tales of Bacterial Effectors" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Claude Parsot (Institut Pasteur)
"Functional analysis of Shigella flexneri type III secretion effectors" |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:20 am | Peter Sebo (Institute of Microbiology of the Academy of Sciences of the Czech Republic)
"Fooling the antigen-presenting phagocyte: Receptor binding and subversive signaling of Bordetella adenylate cyclase" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Ken Bradley (UCLA)
"Identification of host factors required for sensitivity to bacterial toxins" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | Joseph T. Barbieri (Medical College of Wisconsin)
“Carleen M. Collins: A Life in Science” |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CELLULAR MICROBIOLOGY AND PATHOGENESIS |
7:30 pm - 7:45 pm | Discussion Leader: Craig Roy (Yale University) |
7:45 pm - 8:10 pm | Ralph Isberg (Tufts University / HHMI)
"Pathway analysis of proteins translocated into host cells by Legionella pneumophila" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Alejandro Aballay (Duke University)
"Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Samuel Miller (University of Washington)
"Regulation of Rho GTPases and phagosome tubulation by Salmonella effector proteins" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | REGULATORY MECHANISMS IN BACTERIAL PATHOGENS |
9:00 am - 9:15 am | Discussion Leader: Andrew Camilli (Tufts University / HHMI) |
9:15 am - 9:40 am | Matt Waldor (Harvard University)
"Cell-to-cell communication regulates Vibrio cholerae cell size and shape" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Heran Darwin (New York University)
"A ubiquitin-like modification for protein degradation in Mycobacterium" |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Stephen Lory (Harvard University)
"Post-transcriptional regulation of virulence gene expression in Pseudomonas aeruginosa" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Virginia Miller (University of North Carolina, Chapel Hill)
"Yersinia enterocolitica and Yersinia pestis RovA regulons: psa and myf operons as a case history" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Eric Skaar (Vanderbilt University)
"The adaptive response of Staphylococcus aureus to growth in vertebrate blood" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | PHAGE AND PATHOGEN GENOME EVOLUTION |
7:30 pm - 7:45 pm | Discussion Leader: John Mekalanos (Harvard University) |
7:45 pm - 8:10 pm | Andrew Camilli (Tufts Medical School/HHMI)
"Lytic phage and the VBNC state limit transmission of cholera" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | David Friedman (University of Michigan)
"Prophage induction and pathogenicity of enterohemorrhagic E. coli" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Jeffrey F. Miller (UCLA)
"Mutagenic retrohoming and the evolution of parasite-host interactions" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | STRUCTURAL BIOLOGY INSIGHTS INTO MICROBIAL PATHOGENESIS |
9:00 am - 9:15 am | Discussion Leader: Samuel Miller (University of Washington) |
9:15 am - 9:40 am | Partho Ghosh (University of California-San Diego)
"Virulence and crossreactivity of Group A Streptococcus M1 protein" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Bryan Krantz (University of California - Berkeley)
"Anthrax toxin assembly & translocation - an interplay of form & function" |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Feng Shao (National Institute of Biological Sciences, Beijing)
"The MAPK-specific Phosphothreonine Lyase Activity of a Bacterial Type III Effector Family" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Christine Szymanski (National Research Council of Canada)
"Campylobacter jejuni glycosylation - from structure to pathogenesis" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Michelle Dunstone (Monash University)
"A common fold mediates bacterial attack and vertebrate defense" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | TRANSLATING KNOWLEDGE FROM PATHOGENESIS RESEARCH |
7:30 pm - 7:45 pm | Discussion Leader: Harry Mobley (University of Michigan) |
7:45 pm - 8:10 pm | Thomas Dubensky (ANZA Therapeutics)
"Translating Pathogenesis into Vaccine Development: Harnessing the Immunologic Potency of L. monocytogenes to Address Acute Medical Needs" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Mario Feldman (University of Alberta)
"Bacterial glycoproteins and their applications in biotechnology" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | R.E.W. Hancock (University of British Columbia)
"Innate defense regulators as a new anti-infective strategy" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MICROBIAL INFECTION MECHANISMS |
9:00 am - 9:15 am | Discussion Leader: Andreas Baumler (University of California - Davis) |
9:15 am - 9:40 am | Joan Mecsas (Tufts University)
"Role of Yersinia Yops in mouse infections" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | David Hendrixson (University of Texas-Southwestern Medical School)
"Colonization dynamics of Campylobacter jejuni in the natural avian host" |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:10 am | Manuela Raffatellu (University of California, Irvine)
"TH-17 cytokines orchestrate the mucosal barrier to Salmonella" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Padmini Salgame (UMDNJ)
"Helminth Modulation of Tuberculosis" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Karen Guilleman (University of Oregon)
"Keeping the peace: regulation of inflammatory responses to the microbiota in the zebrafish intestine" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | IMMUNITY AND IMMUNOPATHOGENESIS |
7:30 pm - 7:45 pm | Discussion Leader: Mary O'Riordan (University of Michigan) |
7:45 pm - 8:10 pm | Alice Prince (Columbia University)
"Staphylococcus aureus protein A activation of epithelial signaling cascades" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Egil Lien (University of Massachusetts)
"Evasion of innate immunity and the evolution of a highly virulent pathogen" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Vojo Deretic (University of New Mexico)
"Autophagy in immunity and inflammation - from TB to Crohn's Disease" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |