SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Talks: Microbial Toxins and Pathogenicity |
7:40 pm - 7:50 pm | Discussion Leader: Michele Swanson (University of Michigan) |
7:50 pm - 8:25 pm | Gisou van Der Goot (EPFL)
"Pore-forming bacterial toxins: from structure to cellular responses" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:15 pm | Carl Nathan (Weill Cornell Medical College)
"Chemotherapy of Infectious Disease Based on Host-Pathogen Interactions"
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9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Action and Targeting of Toxins |
9:00 am - 9:15 am | Discussion Leader: Klaus Aktories (Uni Freiburg) |
9:15 am - 9:40 am | Karla Satchell (Northwestern University)
"MARTX toxins of Vibrios"
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9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Steven Blanke (University of Illinois-UC)
"Taking the Red Pill: Pathogen Manipulation of the Mitochondrial Matrix" |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Group Photo / Coffee Break |
10:50 am - 11:15 am | Juliane Bubeck Wardenburg (University of Chicago)
"Lassoing the host: cell and tissue-specific consequences of intoxication by S. aureus alpha-hemolysin"
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11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Thijn Brummelkamp (Netherlands Cancer Institute)
"Haploid Genetic Screens in Human Cells to Identify Host Factors used by Pathogens"
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11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Bryan Krantz (UC Berkeley)
"Trafficking and transport: new molecular mechanisms of anthrax toxin regulation"
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12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Regulatory Mechanisms of Bacterial Pathogens |
7:30 pm - 7:45 pm | Discussion Leader: D. Scott Merrell (Uniformed Services University)
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7:45 pm - 8:10 pm | William Navarre (University of Toronto)
"Elongation Factor P and Translational Control of Bacterial Virulence"
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8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Heran Darwin (New York University)
"Out of the Blue: Mycobacterium tuberculosis Copper Resistance"
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8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:15 pm | Matt Waldor (Harvard)
"The German E. coli HUS outbreak strain: lessons from single-model real time DNA sequencing and an animal model"
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9:15 pm - 9:25 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Host-Pathogen Interactions |
9:00 am - 9:15 am | Discussion Leader: Virginia Miller (University of North Carolina) |
9:15 am - 9:40 am | Eric Skaar (Vanderbilt)
"Bacterial strategies to evade nutritional immunity"
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9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Andreas Baumler (UC Davis)
"How the host response feeds enteric pathogens and commensal Enterobacteriaceae"
|
10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Victor Torres (New York University)
"Staphylococcus aureus bi-component toxins: pore-forming toxins that selectively target the host immune surveillance"
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11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Anthony Richardson (University of North Carolina)
"Newly Recognized Host Factors Required for Clearance of Staphylococcus aureus Skin Infections"
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11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Denise Monack (Stanford University School of Medicine)
"Salmonella persistence is controlled by a host regulator of fatty acid metabolism PPARdelta" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Genetic Variation in Pathogens |
7:30 pm - 7:45 pm | Discussion Leader: Howard Ochman (Yale) |
7:45 pm - 8:10 pm | H. (Hank) Steven Seifert (Northwestern University)
"Interplay between transcription, an alternative DNA structure, and homologous recombination promotes immune evasion in the pathogenic Neisseria" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Roy Kishony (Harvard)
"Microbial evolution within human host"
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8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Sebastien Gagneux (Swiss Tropical & Public Health Institute)
"Parallel evolution of tuberculosis and modern humans"
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9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Innate Immunity and Pathogen Strategies |
9:00 am - 9:15 am | Discussion Leader: Mary O'Riordan (University of Michigan) |
9:15 am - 9:40 am | Dan Portnoy (UC Berkeley)
"In search of a unifying hypothesis that explains innate immune responses to intracellular pathogens"
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9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Lynda Stuart (Mass General/Harvard)
"Effector-triggered Immunity in Metazoan Host Defense"
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10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Roger Innes (Indiana University)
"Indirect Recognition of Pathogen Effectors by Plant NOD-Like Receptors" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Russell Vance (UC Berkeley)
"Cytosolic sensing of bacteria by inflammasomes"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Chris Sassetti (University of Massachusetts Medical School)
"Nitric oxide controls tuberculosis immunopathology"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Microbiome in Health and Disease |
7:30 pm - 7:45 pm | Discussion Leader: Lora Hooper (University of Texas Southwestern) |
7:45 pm - 8:10 pm | Sarkis Mazmanian (California Institute of Technology)
"Learning to tolerate our microbial self"
|
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Wendy Garrett (Harvard)
"Insights into Colitogenic and Beneficial Keystone Species from Experimental Colitis"
|
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Eric Pamer (Sloan Kettering)
"Antibiotics, the intestinal microbiota and innate immune defense against infection"
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9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Hijacking of Cell Function |
9:00 am - 9:15 am | Discussion Leader: Zhao-Qing Luo (Purdue University) |
9:15 am - 9:40 am | Craig Roy (Yale)
"Modulation of host cell functions by the Dot/Icm system"
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9:40 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Stephane Meresse (Centre d'Immunologie de Marseille-Luminy)
"Involvement of late effector proteins in Salmonella virulence"
|
10:15 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Christoph Dehio (Basel Institute)
"Effector functions of Bartonella type IV secretion substrates"
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11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Raphael Valdivia (Duke University Medical Center)
"A complex network of early effectors is translocated during Chamydia entry into host cells"
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11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Zachary Dalebroux (University of Washington)
"Identification of a cardiolipin binding protein critical for the PhoPQ-induced permeability barrier of Salmonella" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Anat A. Herskovitz (University of Tel Aviv)
"Phage mediated control of L. monocytogenes virulence" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Perspectives: The Future of Microbe-Host Interaction Studies |
7:30 pm - 7:40 pm | Discussion Leader: Samuel Miller (U. Washington) |
7:40 pm - 8:20 pm | B. Brett Finlay (University of British Columbia)
"The role of the microbiota on enteric pathogens"
|
8:20 pm - 8:30 pm | Discussion |
9:10 pm - 9:20 pm | Cliff Barry (NIAID)
"In vivo imaging of tuberculosis; the dynamics of a chronic disease"
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9:10 pm - 9:20 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |