Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Microbial Toxins and Pathogenicity |
| Discussion Leader: Andrew Camilli (Tufts University School of Medicine, USA) |
7:40 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:35 pm | Pascale Cossart (Pasteur Institute, France) "Listeria monocytogenes: A Unique Model in Infection Biology" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Aaron Whiteley (University of California, Berkeley, USA) "Why Is the PAMP Cyclic Di-AMP Essential in Listeria monocytogenes?" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Cara Mozola Forsberg (University of Washington, USA) "What P. aeruginosa Traits Promote Chronic Infection of CF Airways?" |
9:25 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Toxins - Action, Targeting and Structure |
| Discussion Leader: Joseph Barbieri (Medical College of Wisconsin, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Borden Lacy (Vanderbilt University School of Medicine, USA) "Structure and Function of Clostridium difficile Toxins, TcdA and TcdB" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Neal Alto (University of Texas Southwestern Medical Center, USA) "The Biochemistry of Immune Suppression by Bacterial Pathogens" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Group Photo / Coffee Break |
10:45 am - 11:10 am | Jorge Galan (Yale School of Medicine, USA) "Salmonella typhi's Typhoid Toxin" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Jimmy Ballard (University of Oklahoma Health Sciences Center, USA) "Exploring Variant Forms of Clostridium difficile TcdB" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | Seema Mattoo (Purdue University, USA) "From Bacterial Pathogens to ER Homeostasis: Fic Proteins in Cellular Signalling" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
3:00 pm - 4:00 pm | Power Hour |
| The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring. |
| Organizer: Heran Darwin (New York University School of Medicine, USA) |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Regulation of Virulence |
| Discussion Leader: Peggy Cotter (University of North Carolina at Chapel Hill, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Theresa Koehler (McGovern Medical School, University of Texas Health Science Center at Houston, USA) "What Does the Phophoenolpyruvate Phosphotransferase System Have to Do with Bacillus anthracis Virulence?" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Victoria Stone (University of California, Santa Cruz, USA) "Control of Yersinia Virulence Factor Expression and Pathogenesis by the Iron Sulfur Cluster Transcription Factor IscR" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Melanie Blokesch (École Polytechnique Fédérale de Lausanne, Switzerland) "The Yin and Yang of Type VI Secretion Regulation in Pandemic Vibrio cholerae" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Pathogenesis |
| Discussion Leader: Beth McCormick (University of Massachusetts Medical School, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Arturo Zychlinsky (Max Planck Institute for Infection Biology, Germany) "Antimicrobial Activity of Neutrophils" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Joan Mecsas (Tufts University School of Medicine, USA) "Interactions Between Yersinia and Innate Immune Cells" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Sarah Fortune (Harvard T.H. Chan School of Public Health, USA) "Identifying Determinants of the Outcome of M. tuberculosis Infection Through Single Cell Analyses" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Michael Bachman (University of Michigan, USA) "Insights into Klebsiella pneumoniae Pathogenesis from Patients and Their Animal Models" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Joanne Engel (University of California, San Francisco, USA) "Defining the Chlamydia Inclusion Membrane Protein-Host Protein Interactome" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Pathogen Evolution |
| Discussion Leader: William Goldman (University of North Carolina at Chapel Hill, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Nels Elde (University of Utah, USA) "Experimental Evolution of Pathogen Populations" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Kim Seed (University of California, Berkeley, USA) "Fighting with Phages: How Epidemic Vibrio cholerae Defends Against Viral Attack" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Wyndham Lathem (Feinberg School of Medicine, Northwestern University, USA) "From Mild to Murderous: How Yersinia pestis Evolved into an Efficient Killer" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Basics of Bacterial Pathogens |
| Discussion Leader: Heran Darwin (New York University School of Medicine, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Miriam Braunstein (University of North Carolina at Chapel Hill, USA) "Unraveling the Role of the SecA2 Pathway in Mycobacterium tuberculosis in Macrophages" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Michael Federle (University of Illinois at Chicago, USA) "Social Appearances: Quorum Sensing Control of the Cell Envelope of Streptococcus pyogenes" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Nina Salama (Fred Hutchinson Cancer Research Center, USA) "Bacterial Adaptations for Life in the Stomach" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Andrew Darwin (New York University School of Medicine, USA) "Pushing the Envelope in Bacterial Pathogenesis" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Vincent Lee (University of Maryland, College Park, USA) "Discovery of Signaling Nucleotide Receptors and Their Inhibitors" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Close Encounters with the Host Cell |
| Discussion Leader: Mary O'Riordan (University of Michigan Medical School, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Barbara Kazmierczak (Yale University, USA) "Phenotypic Heterogeneity in Pseudomonas Pathogenesis" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Raphael Valdivia (Duke University Medical Center, USA) "Mechanisms of Cell Survival in Chlamydia Infected Cells" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Alison Criss (University of Virginia, USA) "Flirting with Disaster: How Neisseria gonorrhoeae Survives Encounters with Neutrophils" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Innate Immune Responses and Pathogenesis |
| Discussion Leader: Manuela Raffatellu (University of California, Irvine, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Jyothi Rengarajan (Emory University, USA) "Mycobacterium tuberculosis Modulation of Innate-Adaptive Crosstalk" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | David Underhill (Cedars-Sinai Medical Center, USA) "Innate Immune Recognition of Bacterial Cell Walls" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Jorge Henao-Mejia (University of Pennsylvania, USA) "Regulation of Immune Host Defense by Novel Long Non-Coding RNAs" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Ken Cadwell (New York University School of Medicine, USA) "Autophagy and Enteric Bacterial Infections" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Sunny Shin (University of Pennsylvania, USA) "Overcoming Bacterial-Encoded Virulence Activities to Initiate Innate Immune Defense" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Keynote Session: Perspectives on the Future of Host-Pathogen Interaction Research |
| Discussion Leader: Karen Ottemann (University of California, Santa Cruz, USA) |
5:30 pm - 5:40 pm | Introduction by Discussion Leader |
5:40 pm - 6:25 pm | Eric Skaar (Vanderbilt University, USA) "The Intersection of Nutrition and Infection at the Host-Pathogen Interface" |
6:25 pm - 6:40 pm | Discussion |
6:40 pm - 6:55 pm | Lillian Juttukonda (Vanderbilt University, USA) "Dietary Manganese and the Host Protein Calprotectin Promote Staphylococcal Infection of the Hear" |
6:55 pm - 7:00 pm | Discussion |
7:00 pm - 7:15 pm | Damien Keogh (SCELSE, Nanyang Technological University, Singapore) "Enterococcus faecalis Powers Biofilm Formation Through Extracellular Electron Transfer of Iron" |
7:15 pm - 7:20 pm | Discussion |
7:20 pm - 7:30 pm | General Discussion |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |