Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Novel Catalytic Strategies
7:40 pm - 8:05 pm
"Development of Novel Non-Precious Metal Catalyzed Methodologies for the Synthesis of Biologically Active Heterocyclic Compounds"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Transition Metal-Catalyzed Amination and Amidation Reactions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Stereoselective Catalysis of Nucleophilic Substitution Reactions"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Discovery of Novel Natural Products
9:00 am - 9:30 am
"New Approaches for the Discovery of Microbial Natural Products"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Discovery of Novel Bioactive Polyketides/Non-Ribosomal Peptides from Microbes"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Harnessing Genomic Information to Engineer the Biosynthesis of Natural Products"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Culture Independent Approaches for the Discovery of New Bacterial Metabolites"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Innovations in Drug Discovery
7:30 pm - 8:00 pm
"Correcting Disregulated Translation: Disciplined Structure-Based Inhibitor Design of eFT508 for the Treatment of Cancer"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Scaling Highly Potent Bifunctional Duocarmycin Derivatives for Treatment of Cancer"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Bioactivity and Mechanism of Action of N-Docosahexaenoylethanolamine Derivatives in Neuronal Development"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Natural Products Biosynthesis
9:00 am - 9:30 am
"Discovery and Engineering of Plant Chemistry"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Harnessing the Biosynthetic Capabilities of Marine Actinomycetes"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Harnessing Plant Metabolic Diversity"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Engineered Polyketide Synthases for Production of Commodity and Specialty Chemicals"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Chemistry, Structure and Function of Complex Glycosides
7:30 pm - 8:00 pm
"New Chemical Biology Methods to Uncover the Functional Roles of Glycosylation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Chemoenzymatic Synthesis of Glycoproteins for Probing Functions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Chemistry to Explore and Exploit Microbial Carbohydrates for Health and Disease"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Structurally Complex Natural Products Synthesis
9:00 am - 9:30 am
"Synthesis of Complex Terpenes from Simple Precursors"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Chemical Synthesis of Secondary Metabolites"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
"Total Synthesis of Polycyclic Natural Products"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Building Bridges: Strategies for the Synthesis of Complex Polycyclic Natural Products"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Rare and Neglected Disease Research
7:30 pm - 8:00 pm
"Collaborative Virtual Screening to Boost Neglected Tropical Disease Drug Discovery"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Discovery of Sequanamycin Derivatives as Potent Oral Anti-Tuberculosis Agents"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Bogged Down: An Ecology-Inspired Search for Novel Antituberculars"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Approaches to the Study of Bioactive Natural Products
9:00 am - 9:30 am
"Exploring the Master Regulators of Microbial Behavior"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Marine Natural Products Synthesis: A Driving Force for Chemical and Biological Discovery"
10:10 am - 10:20 am
Discussion
10:20 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Total Synthesis of Neurologically Active Terpenoid Natural Products"
11:00 am - 11:10 am
Discussion
11:10 am - 11:40 am
"Syntheses Through 'Seeding and Growing' Strategy Inspired by Molecular Pattern Recognition"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
"Leveraging Carbene Catalysis for Complex Synthesis"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Strategies and Tactics for Chemical Synthesis
7:30 pm - 7:50 pm
"Unlocking Catalytic Promiscuity with Light: Non-Natural Free Radical Chemistry Within a Protein Active Site"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:30 pm
"From Radical Cations to Microelectrode Arrays to the Valorization of Lignin: Using Principles in Physical Organic Chemistry to Guide Electrochemical Solutions to Modern Synthetic Challenges"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
"New Photoredox Reactions"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure