Sunday, July 6
Evening
Matthew Shair, Discussion Leader |
2:00 | Registration Begins | |
6:00 | Dinner, Gilmore Hall | |
7:30 | Welcome | Jon Clardy |
8:00 | Total Synthesis of Keramamide | Peter Toogood |
8:30 | Design, Development and Applications of Transition-Metal Complexes and Raegents in Asymmetric Synthesis | Erick Carreira |
9:30 | Reception | |
Monday, July 7
Morning
Julie Lee, Discussion Leader |
9:00 | Cooperativity in the Action of Glycopeptide Antibiotics | Dudley H. Williams |
10:00 | Our Mutualist Friends: Metabolites from Bacteria in the Agroecosystem | Jo Handelsman |
10:30 | Break | |
Gerald Hammond, Discussion Leader |
11:00 | Microbial Resistance in the Natural Product Biosynthetic Continuum | David H. Sherman |
11:30 | The Chemical Wizardry or Insects | Tom Eisner |
Afternoon
12:30 | Lunch | |
4:30 | Poster Session 1 | |
6:00 | Dinner | |
Evening
Amy Wright, Discussion Leader |
7:30 | Novel Examples of Biodiversity and Chemical Diversity in the Search for Medical Agents | Michael Goetz |
8:00 | Anticancer Agents from Cultured and Collected Marine Organisms | William Fenical |
9:00 | SAR by NMR: A New Method for Drug Discovery | Suzanne Shuker |
9:30 | Total Synthesis of Duocarmycin SA Analogue, LY307918 | Vinod Patel |
9:45 | Novel Antifungal Agents from Deep Water Sponges | Amy E. Wright |
Tuesday, July 8
Morning
Spencer Knapp, Discussion Leader |
8:30 | Antimicrobial Peptides from Primitive Fish: Biological Role of Brominated Tryptophan in Host Defense Peptides | Ann E. Shinnar |
9:00 | Photo Session Break | |
9:15 | Organic Chemistry on Chemical Surfaces: Engineering New Cell Surface Chemistry for Selective Tumor Targeting | Carolyn Bertozzi |
Rebecca Cowan Hoye, Discussion Leader |
10:30 | Genetic Manipulation of teh Structure of Complex Polyketides: What Are We Still Missing? | Leonard Katz |
11:30 | Solid-Phase Chemical Ligation | Steven Kent |
Afternoon
12:30 | Lunch | |
4:30 | Poster Session 2 | |
6:00 | Dinner | |
Evening
James Whitesell, Discussion Leader |
7:30 | Amyloid Formation in Alzheimer's Disease | Peter T. Lansbury |
8:30 | Conus Peptides: From Genes to Natural Products | Baldomero Olivera |
9:30 | Yeast Genetics and Peptide Libraries: A Budding Alliance | Thea C. Norman |
9:45 | Characterization of Peptide Synthetase Genes from Cyanobacteria | Kaarina Sivonen |
Wednesday, July 9
Morning
Philip DeShong, Discussion Leader |
8:30 | Design and Construction of a General-Binding Scaffold: Application to a Peptidomimetic Anti-Integrin Library Based on RGB | David J. Austin |
9:00 | Structural, Synthetic, and Biomechanistic Studies of the Pateamines: Novel, Immunosuppressive Dilactone Macrolides from the Marine Sponge Mycale sp. | Daniel Romo |
9:30 | Synthetic and Mechanistic Studies to Probe the Sequence Selective DNA Recognition of the Duocarmycins and Bleomycin A2 | Dale Boger |
10:30 | Break | |
Ellen Baxter, Discussion Leader |
11:00 | Carbonyl Chemistry of Ascomycin | Kathy Rupprecht |
11:30 | Catalytic Asymmetric Synthesis of Natural Products | Masakatsu Shibasaki |
Afternoon
12:00 | Synthetic Studies Toward the Reveromycins | Emmanuel A. Theodorakis |
12:30 | Lunch | |
4:30 | Poster Session 3 | |
6:00 | Dinner | |
Evening
Michael Lewis, Discussion Leader |
7:30 | Receptor and Function Selective Retinoids - Keys to Better Retinoid Therapeutics | Roshantha A.S. Chandraratna |
8:00 | Secondary Structure Templated Libraries in Drug Discovery | Michael Kahn |
8:30 | Recent Developments in the Synthesis and Functionality of Natural Products | Samuel Danishefsky |
9:30 | Tandem Asymmetric Transformations: Coupling of an Asymmetric 1,2-Migration From a Higher Order Zincate with Long-Range Stereoselectivity in a Homoaldol Reaction | Joseph D. Armstrong, III |
9:45 | Stereoselective Synthesis of Biologically Important Cyclic Ether Containing Natural Products via Intramolecular Radical Cyclizations | P. Andrew Evans |
Thursday, July 10
Morning
Ann Shinnar, Discussion Leader |
8:30 | High-Sensitivity Micro-Immunoassay Using a Novel Upconverting Phosphor Reporter | Robert R. Webb |
9:00 | Small Molecular Approaches to Cytoskeleton Biology | Tim Mitchison |
10:00 | Minimization of a Protein Binding Domain | Andrew Braisted |
10:30 | Break | |
Phillip Crews, Discussion Leader |
11:00 | Marine Pyrido [2,3,4-kl]acridines; Structure and Synthesis | Yoel Kashman |
11:30 | Pharmaceutically Useful Compounds from Marine Species | Ken Rinehart |
Afternoon
12:30 | Lunch | |
2:00 | Annual Softball Game: Academic All-Stars vs. Industrial All-Stars | |
6:00 | Dinner | |
Evening
R.P. Volante, Discussion Leader |
7:30 | Business Meeting | |
8:00 | Using and Discovering Small Molecule Ligands for Chemical Genetic Experiments | Stuart L. Schreiber |
9:30 |
PARTY! | |
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