| Sunday, July 30 |
| 2:00 pm | Conference Registration |
| 6:00 pm | Dinner |
| 7:30 pm | Chair's Welcome - Rob Webb (IntraBiotics) |
| Sunday Evening Session: Methodology/Total Synthesis |
| Discussion Leader: Rich Taylor (Notre Dame) |
| 7:50 pm | Jim Leighton (Columbia) - Invited Short Talk:
"New Olefin Carbonylation Reactions
for Organic Synthesis" |
| 8:05 pm | Discussion |
| 8:15 pm | Scott Miller (Boston College) - Invited Short Talk:
"Discovery of Minimal Peptides for
Asymmetric Catalysis and Organic
Synthesis" |
| 8:30 pm | Discussion |
| 8:40 pm | Larry Overman (UC Irvine) - "New Methods for Ring Formation and
Their Application in Natural Products
Total Synthesis" |
| 9:30 pm | Chair's Reception |
| Monday, July 31 |
| 7:30 am | BREAKFAST |
| Monday Morning Session: Total Synthesis |
| Discussion Leader: Jim Leahy (Exelixis Pharmaceuticals) |
| 8:45 am | Dan Comins (NC State) - "Chiral Dihydropyridones as Intermediates
for Alkaloid Synthesis" |
| 9:20 am | Discussion |
| 9:30 am | Randy Halcomb (Colorado) - "Investigations of the Synthesis of Zaragozic Acid and Phomactin" |
| 9:50 am | Discussion |
| 10:00 am | GROUP PHOTO SESSION |
| Monday Mid-Morning Session: Isolation/Mechanistic Studies |
| Discussion Leader: Sean Brady (Cornell University) |
| 10:30 am | Daisuke Uemura (Nagoya) - "Chemistry of Biologically and Physiologically
Intriguing Phenomena" |
| 11:10 am | Discussion |
| 11:20 am | Nicola Pohl (Stanford) - Invited Short Talk:
"Engineering Polyketide Synthases" |
| 11:35 am | Discussion |
| 11:40 am | Chris Ireland (Utah) - "Marine Natural Products, Structure
and Function" |
| 12:20 pm | Discussion |
| 12:30 pm | LUNCH |
| 1:30 pm | FREE TIME |
| 4:30 pm | Poster Session #1 |
| 6:00 pm | DINNER |
| Monday Evening Session: BioOrganic Chemistry |
| Discussion Leader: Mike Luzzio (Pfizer) |
| 7:30 pm | David VanVranken (UC Irvine) - Invited Short Talk:
"Biaryl Peptide Crosslinks and
Natural Products Total Synthesis" |
| 7:45 pm | Discussion |
| 7:50 pm | Carolyn Bertozzi (UC Berkeley) - "Organic Chemistry on Cell Surfaces" |
| 8:30 pm | Discussion |
| 8:40 pm | Sam Danishefsky (Columbia/Sloan-Kettering) - "On the Awesome Power of Chemical
Synthesis" |
| Tuesday, August 1 |
| 7:30 am | BREAKFAST |
| Tuesday Morning Session: Analytical/Instrumentation |
| Discussion Leader: Reyna Simon (IntraBiotics Pharmaceuticals)
|
| 8:45 am | Dave Detlefson (Bristol-Myers Squibb) - "NMR in Pharmaceutical Research and
Development: Too Much, Too Late" |
| 9:15 am | Discussion |
| 9:20 am | Alan Marshall (Florida State University) - "New Mass Spetrometric Techniques for
Identification, Structural, and Functional
Analysis of Natural Products" |
| 9:50 am | Discussion |
| 10:00 am | BREAK |
| Tuesday Mid-Morning Session: Methodology/Total Synthesis |
| Discussion Leader: Joe "Chili Dog" Armstrong (Merck) |
| 10:20 am | Steve King (Abbott Laboratories) - "A Catalytic Enantioselective Conjugate Addition.
Stereoselective Synthesis of Endothelin
Antagonists" |
| 10:50 am | Discussion |
| 10:55 am | Jim Panek (Boston University) - "Studies on the Synthesis of Complex
Natural Products" |
| 11:30 am | Discussion |
| 11:40 am | Jim Marshall (University of Virginia) - "Asymmetric Synthesis with Chiral Allenyl
Metal Compounds" |
| 12:20 pm | Discussion |
| 12:30 pm | LUNCH |
| 1:30 pm | FREE TIME |
| 4:30 pm | Poster Session #2 |
| 6:00 pm | DINNER |
| Tuesday Evening Session: Isolation/Mechanistic Studies |
| Discussion Leader: Jennifer Pace (Abbott Laboratories) |
| 7:30 pm | Carrie Wager (Utah) - "The Total Synthesis of Rhizoxin D" |
| 7:45 pm | Discussion |
| 7:50 pm | Gary Strobel (Montana State) - "Gifts from the Rainforest" |
| 8:30 pm | Discussion |
| 8:40 pm | Rod Croteau (Washington State) - "Terpenoid-Based Defenses in Conifers" |
| Wednesday, August 2 |
| 7:30 am | BREAKFAST |
| Wednesday Morning Session: Medicinal Chemistry |
| Discussion Leader: Deb Evrard (Wyeth-Ayerst) |
| 8:45 am | Ving Lee (Microcide) - "Getting Pumped about Efflux" or "Adding
New Life to Older Antibiotics-Efflux
Pump Inhibitors" |
| 9:15 am | Discussion |
| 9:25 am | Wendy Young (Axys Pharmaceuticals) - "Zinc Potentiated Inhibition: The
Xa Files - The Truth Is Out There"
|
| 9:50 am | Discussion |
| 10:00 am | BREAK |
| Wednesday Mid-Morning Session: Total Synthesis |
| Discussion Leader: Mike Greco (RW Johnson Pharmaceutical Research Institute) |
| 10:20 am | Tom Hoye (University of Minnesota) - "Natural Product Structure and
Synthesis Studies" |
| 11:00 am | Discussion |
| 11:10 am | Ron DuBois (NIH) - "Navigating the N.I.H. Peer Review System" |
| 11:30 am | Discussion |
| 11:40 am | Victor Snieckus (Queens University) - "Metalation: A Point of Departure for New
Bioactive Molecule and Natural Product
Constructs" |
| 12:20 pm | Discussion |
| 12:30 pm | LUNCH |
| 1:30 pm | FREE TIME |
| 4:30 pm | Poster Session #3 |
| 6:00 pm | DINNER |
| Wednesday Evening Session: Isolation/Total Synthesis |
| Discussion Leader: Claire Gutteridge (Merck) |
| 7:30 pm | Michael Calter (Rochester) - Invited Short Talk:
"Using Ketenes to Make Polypropionates" |
| 7:45 pm | Discussion |
| 7:50 pm | Steve Weinreb (Penn State) - "Studies in Alkaloid Total Synthesis" |
| 8:30 pm | Discussion |
| 8:40 pm | John Daly (NIH) - "The Frog-Arthropod Connection: Biologically
Active Alkaloids" |
| Thursday, August 3 |
| 7:30 am | BREAKFAST |
| Thursday Morning Session: New Technologies/Methodology |
| Discussion Leader: Mike Curtin (Abbott Laboratories) |
| 8:45 am | Matt Shair (Harvard) - "Target-Oriented Synthesis and Diversity-
Oriented Screens for Organic Synthesis" |
| 9:15 am | Discussion |
| 9:25 am | David MacMillan (UC Berkeley) - Invited Short Talk:
"Development of a New
Acid Catalyzed Claisen Rearrangement and
Application to Complex Target Synthesis" |
| 9:50 am | Discussion |
| 10:00 am | BREAK |
| Thursday Mid-Morning Session:
Total Synthesis/Methodology |
| Discussion Leader: Yvonne Shimshock (Pharmacopaeia) |
| 10:20 am | Suzy Shuker (Georgia Tech) - "Catalyst Discovery Through Synthesis
and Screening of Combinatorial Libraries" |
| 10:45 am | Discussion |
| 10:55 am | Steve Olson(Merck) - Short Talk:
"Synthesis of Coumermycin Analogs as potential mediators of signal transduction" |
| 11:15 am | Discussion |
| 11:25 am | Alison Hulme (Edinborough) - Invited Short Talk:
"Iminosugars and Beyond" |
| 11:50 am | Discussion |
| 12:00 pm | Jeff De Brabander (UTSWMC) - Short Talk: "Anti-tumor macrolide (-)-Salicylihalamide A" |
| 12:20 pm | Discussion |
| 12:30 pm | LUNCH |
| 2:00 pm | Annual Academia-Industry Softball Game |
| 6:00 pm | DINNER |
| 7:30 pm | Rob Webb (IntraBiotics) - Conference Business :
Election of Vice-Chair for 2002
Presentation of Softball Awards
Conference Evaluation Forms
|
| Thursday Evening Session:
BioOrganic Chemistry |
| Discussion Leader: Agnes Kim-Meade (Schering-Plough) |
| 7:45 pm | Jacqueline Gervay-Hague (Arizona) - "Carbohydrate Based Chemotherapeutics and
Drug Delivery Systems" |
| 8:25 pm | Discussion |
| 8:35 pm | Stuart Schreiber (Harvard) - "Towards A Chemical Genetics" |
| Friday, August 4 |
| 7:30 am | BREAKFAST |
| 9:00 am | BUS TO BOSTON/LOGAN AIRPORT |
