| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Natural Products |
| 7:30 pm - 7:45 pm | Michael J. Luzzio (Pfizer Global Research and Development)
Chair's Opening Remarks |
| Discussion Leader: David E. Uehling (Glaxo Smithkline) |
| 7:45 pm - 8:25 pm | Erik J. Sorensen (Scripps Research Institute)
"Architectural Self-Construction in Nature and Chemical Synthesis" |
| 8:25 pm - 8:45 pm | Justin Du Bois (Stanford University)
"The Evolution of New Oxidation Reactions for Target-Directed Synthesis" |
| 8:45 pm - 9:30 pm | Larry E. Overman (University of California, Irvine)
"Total Synthesis of Polycyclic Natural Products: Recent Studies" |
| 9:30 pm | Chair's Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Natural Products |
| Discussion Leader: Katherine Lee (Wyeth) |
| 9:00 am - 9:45 am | James A. Marshall (University of Virginia)
"Synthesis of Polyketide Natural Products" |
| 9:45 am - 10:20 am | Amy E. Wright (Harbor Branch Oceanographic Institute)
"New Cytotoxic Compounds from Deep-Sea Marine Invertebrates" |
| 10:20 am - 10:45 am | Coffee Break |
| Discussion Leader: Joseph D. Armstrong (Merck Research Laboratories)
|
| 10:45 am - 11:30 am | Jin K. Cha (Wayne State University)
"New Synthetic Methods for Medium-sized Carbocycles" |
| 11:30 am - 11:50 pm | Jeffrey Johnston (Indiana University)
"Development of Free Radical-Mediated Aryl and Vinyl Amination and Their Use in Alkaloid Synthesis" |
| 11:50 am - 12:10 pm | Victor Behar (Rice University)
"Progress Towards the Total Synthesis of Lactonamycin and Related Type II Polyketides" |
| 12:10 am - 12:30 pm | Michael J. Krische (University of Texas, Austin)
"Catalytic Cycloreductions and Cycloisomerizations: Enones as Latent Enolates" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Natural Products |
| Discussion Leader: David Askin (Merck Research Laboratories)
|
| 7:30 pm - 8:10 pm | Alicia Regueiro-Ren (Bristol Myers Squibb)
"Semisynthetic Epothilone Analogues: Chemistry and Biological Activity" |
| 8:10 pm - 8:50 pm | Richard Versace (Novartis)
"Bengamides: From Sponge to Clinic" |
| 8:50 pm - 9:30 pm | Stephen F. Martin (University of Texas, Austin)
"Recent Advance in the Synthesis of Heterocyclic Natural Products" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Natural Products |
| Discussion Leader: Francis G. Fang (Eisai Research Institute)
|
| 9:00 am - 9:45 am | Tohru Fukuyama (University of Tokyo)
"Synthetic Studies on Heterocyclic Natural Products" |
| 9:45 am - 10:20 am | Michael A. Letavic (Pfizer Global Research and Development)
"Synthesis of Novel 9a-aza-9a-homoerythromycin Antibiotics" |
| 10:20 am - 10:45 am | Coffee Break |
| Discussion Leader: Michael N. Greco (Johnson and Johnson PRD)
|
| 10:45 am - 11:30 am | Viresh H. Rawal (University of Chicago)
"Recent Advances of in Methods and Strategies to Complex Natural Products" |
| 11:30 am - 11:50 pm | Dirk Trauner (University of California, Berkeley)
"New Pericyclic Reactions in Natural Products Synthesis" |
| 11:50 am - 12:10 pm | Tomislav Rovis (Colorado State University)
"Controlling Stereochemistry in Carbon-Carbon Bond Forming Reactions" |
| 12:10 pm - 12:30 pm | Daniel Romo (Texas A&M University)
"Synthetic Studies of Oroidin-Derived Marine Alkaloids" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Natural Products |
| Michael D. Lewis (Eisai Research Institute)Discussion Leader
|
| 7:30 pm - 8:10 pm | Ross A. Miller (Merck Process Research)
"Practical Syntheses of an Second-Generation HIV-Protease Inhibitor" |
| 8:10 pm - 8:50 pm | Rima Al-awar (Eli Lilly)
"Annulated bisindolylmaleimides and indolocarbazoles as kinase inhibitors" |
| 8:50 pm - 9:30 pm | Yoshito Kishi (Harvard University)
"Recent Topics in Natural Products Chemistry" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Natural Products |
| Discussion Leader: Samit K. Bhattacharya (Pfizer Global Research and Development) |
| 9:00 am - 9:45 am | William H. Gerwick (Oregon State University)
"Intriguing Structural Features of Bioactive Marine Cyanobacterial Natural Products" |
| 9:45 am - 10:20 am | Christopher J. Creighton (Johnson and Johnson)
"Design, Synthesis and Conformational Analysis of Novel Scaffolds for Bioorganic Chemistry and Non Covalent Supramolecular Structures" |
| 10:20 am - 10:45 am | Coffee Break |
| Discussion Leader: Joel Morris (Pfizer Global Research and Development)
|
| 10:45 am - 11:30 am | David MacMillan (California Institute of Technology)
"Design of New Catalysis Concepts of Broad Utility to Chemical Synthesis" |
| 11:30 am - 11:50 am | Richard P. Hsung (University of Minnesota)
"A Formal Aza-[3+3] Annulation Strategy for the Total Synthesis of Alkaloids" |
| 11:50 am - 12:10 pm | Bruce F. Molino (Albany Molecular Research)
"Modern Biocatalysis as a Powerful Tool in Drug Discovery and Development" |
| 12:10 pm - 12:30 pm | Gregory R. Dake (University of British Columbia)
"Ring Expansion Reactions to Form Azaspirocyclic Ketones: A Construction of Fasicularin" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 3 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Natural Products |
| Discussion Leader: Ellen W. Baxter (Johnson and Johnson PRD)
|
| 7:30 pm - 8:10 pm | Paul Coleman (Merck Research Laboratories)
"Integrin Antagonists for the Treatment of Osteoporosis" |
| 8:10 pm - 8:55 pm | Tadeusz F. Molinski (University of California, Davis)
"Marine Natural Products-Ligands Matched to Receptors, Enzymes and Ion Channels" |
| 8:55 pm - 9:30 pm | Jeffrey D. Winkler (University of Pennsylvania)
"Synthesis of Natural and Unnatural Products" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Natural Products |
| Discussion Leader: Vincent P. Sandanayaka (Astra Zeneca)
|
| 9:00 am - 9:45 am | David J. Hart (Ohio State University)
"Oxonium Ion and Free Radical Cyclizations: Approaches to Selected Natural Products" |
| 9:45 am - 10:20 am | Nancy I. Totah (Syracuse University)
"Synthesis of Oxadecalin Containing Natural Products" |
| 10:20 am - 10:45 am | Coffee Break |
| Discussion Leader: Michael S. Van Nieuwenhze (University of California, San Diego) |
| 10:45 am - 11:30 am | Henk Hiemstra (University of Amsterdam)
"Studies toward the synthesis and properties of solano-eclepin A, a hatching agent of potato cyst nematodes" |
| 11:30 am - 11:50 am | George F. Majetich (University of Georgia)
"The Use of Tandem Reactions for the Synthesis of Complex Triterpenes" |
| 11:50 am - 12:30 pm | Geneviève Balme (Université Claude Bernard)
"Palladium-Mediated Cascade and Multicomponent Reactions New Route to Heterocyclic Compounds" |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 2:00 pm - 5:00 pm | Annual Academic-Industrial Softball Game |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Natural Products |
| Discussion Leader: Frederick A. Luzzio (University of Louisville)
|
| 7:30 pm - 8:15 pm | Marcus A. Tius (University of Hawaii)
"Synthesis of five-membered rings" |
| 8:15 pm - 8:35 pm | Jeffrey S. Johnson (University of North Caroline at Chapel Hill)
"New Catalytic Chemistry of (Silyloxy) Nitrile Anions" |
| 8:35 pm - 9:30 pm | Ronald C. Breslow (Columbia University)
"Biomimetic Chemistry" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
