| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:10 pm - 7:30 pm | Frederick A. Luzzio (University of Louisville)
Chair’s Welcome and Opening Remarks |
| 7:30 pm - 9:30 pm | TOTAL SYNTHESIS/METHODOLOGY (I) |
| Discussion Leader: Scott R. Gilbertson (University of Texas Medical Branch) |
| 7:30 pm - 8:10 pm | Dieter Enders (Institute of Organic Chemistry, RWTH Aachen)
"Stoichiometric and Catalytic Asymmetric Syntheses of Natural Products" |
| 8:10 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:30 pm | Invited Short Talk: Glenn C. Micalizio (Yale University)
"Group 4 Metals in Polyketide Synthesis" |
| 8:30 pm - 8:35 pm | Discussion |
| 8:35 pm - 9:25 pm | Steven M. Weinreb (Pennsylvania State University)
"Methodology for Alkaloid Synthesis" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm | Chair’s Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 10:30 am | SYNTHESIS/MEDICINAL CHEMISTRY |
| Discussion Leader: Dee Ann Casteel (Bucknell University) |
| 9:00 am - 9:35 am | Gary H. Posner (Johns Hopkins University)
"Trioxanes for Chemotherapy of Malaria and Cancer" |
| 9:35 am- 9:40 am | Discussion |
| 9:40 am -10:10 am | Cynthia A. Parrish (GlaxoSmithKline)
"Simple Molecules in a Complex System: Mechanistically Novel Kinesin Inhibitors" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:30 am | Coffee Break |
| 10:30 am - 12:30 pm | MEDICINAL CHEMISTRY/CHEMICAL BIOLOGY |
| Discussion Leader: Julianne A. Hunt (Merck Research Laboratories) |
| 10:30 am - 11:05 am | Jacquelyn Gervay-Hague (University of California, Davis)
"Facile Synthesis of Immunoresponsive Glycolipid Natural Products: Toward Delineating the CD1d Restricted Activation of NKT Cells" |
| 11:05 am - 11:00 am | Discussion |
| 11:10 am - 11:45 am | Gabriela Chiosis (Sloan-Kettering Institute)
"Discovery and Development of Purine Scaffold Hsp90 Inhibitors" |
| 11:45 am - 11:50 am | Discussion |
| 11:50 am - 12:25 pm | Linda Hsieh-Wilson (California Institute of Technology)
"Decoding the Structure-Activity Relationships of Carbohydrates in the Brain" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TOTAL SYNTHESIS/METHODOLOGY (II) |
| Discussion Leader: Michael B. Smith (University of Connecticut) |
| 7:30 pm - 8:05 pm | Thomas R. Hoye (University of Minnesota)
"Oldies but (Still) Goodies: Steroids, Diels-Alder Reactions and/or Cope Rearrangements" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:45 pm | Victor Snieckus (Queen’s University)
"Directed ortho Metalation-A Point of Departure for Heteroaromatic Manipulation and Modification" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:25 pm | Philip L. Fuchs (Purdue University)
"Synthesis of Hyperpotent Cephalostatin Anticancer Agents" |
| 9:25 pm- 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:35 am | MEDICINAL CHEMISTRY |
| Discussion Leader: Silvina Garcia Rubio (Albany Molecular Research) |
| 9:00 am - 9:35 am | Harold Blair Wood (Merck Research Laboratories)
"Identification of Selective PPARg modulators for Type II Diabetes" |
| 9:35 am- 9:40 am | Discussion |
| 9:40 am - 10:15 am | Joe Shih (Lilly Research Laboratories)
"The Evolution of Lilly Oncology: From Natural Products to Kinase Inhibitors" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Coffee Break |
| 10:35 am - 12:30 pm | MARINE NATURAL PRODUCTS |
| Discussion Leader: Richard W. Fitch (Indiana State University) |
| 10:35 am - 11:10 am | Bill J. Baker (University of South Florida)
"Recent Advances in the Development of the Palmerolides" |
| 11:10 am - 11:15 am | Discussion |
| 11:15 am - 11:45 am | Mark T. Hamann (University of Mississippi)
"The Structure Determination and Lead Optimization of Marine Natural Products From Invertebrate-Associated Bacteria and Dinoflagellates Associated with Harmful Algal Blooms" |
| 11:45 am -11:50 am | Discussion |
| 11:50 am - 12:25 pm | Peter Northcote (Victoria University)
"The Peloruside Story: The Chemical Ecology and Aquaculture of Mycale henscheli" |
| 12:25 pm -12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II/td> |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TOTAL SYNTHESIS/METHODOLOGY (III) |
| Discussion Leader: G.B. Hammond (University of Louisville) |
| 7:30 pm - 8:05 pm | Christina Moberg (Royal Institute of Technology)
"Dual Activation-A Duel Between Rivals" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:45 pm | Arun K. Ghosh (Purdue University)
"Bioactive Natural Products: How They Inspire Our Design of Novel Molecular Probes" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:25 pm | Robert K. Boeckman, Jr (University of Rochester)
"New Developments in Synthetic Methodology with Applications to the Construction of Complex Molecules of Biological Interest" |
| 9:25 pm- 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:30 am | TOTAL SYNTHESIS/METHODOLOGY (IV) |
| Discussion Leader: George F. Majetich (University of Georgia) |
| 9:00 am - 9:20 am | Short Talk: Mohammad Movassaghi (Massachusetts Institute of Technology)
"Total Synthesis of Galbulimima Alkaloids" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Short Talk: Steven L. Castle (Brigham Young University)
"New Methods and Strategies for the Synthesis of Complex Alkaloids" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Short Talk: John D. Chisholm (Syracuse University)
"Synthetic Studies Toward Maoecrystal V" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:35 am | Coffee Break |
| 10:35 am - 12:30 pm | CHEMICAL BIOLOGY/BIOORGANIC CHEMISTRY |
| Discussion Leader: Eriks Rozners (Northeastern University) |
| 10:35 am - 11:05 am | Seiichi P.T. Matsuda (Rice University)
"The Origins of Triterpenoid Skeletal Diversity" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | short Talk: Akira Kawamura (Hunter College)
"Rediscovery of Natural Products Using Genomic Screening" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:25 pm | David E. Cane (Brown University)
"Nature’s Dirty Secrets" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session III |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | TOTAL SYNTHESIS/METHODOLOGY (V) |
| Discussion Leader: Rima Al-Awar (Eli Lilly) |
| 7:30 pm - 8:05 pm | Daniel L. Comins (North Carolina State University)
"Progress toward the Synthesis of Complex Lycopodium Alkaloids" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:45 pm | Stephen Pyne (University of Wollongong)
"Employing the Borono-Mannich Reaction in Natural Products Synthesis" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:25 pm | James M. Cook (University of Wisconsin-Milwaukee)
"General Approach for the Synthesis of Ring A Alkoxy-Substituted Indole Alkaloids via the Asymmetric Pictet-Spengler Reaction" |
| 9:25 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:35 am | PROCESS CHEMISTRY/METHODOLOGY |
| Discussion Leader: Nancy I. Totah (Syracuse University) |
| 9:00 am - 9:35 am | Seble H. Wagaw (Abbott Laboratories)
"The Development of a Scalable Route to the Selective DPP-IV Inhibitor ABT-279" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am -10:15 am | Kevin R. Campos (Merck Research Laboratories)
"Catalytic Asymmetric Reactions in the Synthesis of Complex Drug Targets" |
| 10:15 am - 10: 20 am | Discussion |
| 10:20 am -10:35 am | Coffee Break |
| 10:35 am - 12:30 pm | MEDICINAL CHEMISTRY/ASYMMETRIC SYNTHESIS |
| Discussion Leader: Elizabeth T. Syage (Allergan) |
| 10:35 am - 11:15 am | Robert A. Volkmann (Pfizer)
"Linking Molecular Structure to Biological Response" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:40 am | Short Talk: Anna Chiu (Merck Research Laboratories)
"Enantioselective Desymmetrization by a Miniaturized Enzyme Mimic" |
| 11:40 am -11:45 am | Discussion |
| 11:45 am - 12:25 pm | Philip P. Garner (Case Western Reserve University)
"A Unified Synthetic Approach to the Bioxalomycins and Related Natural (and Unnatural) Products" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 2:00 pm - 5:00 pm | Annual Academic-Industrial Softball Game |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TOTAL SYNTHESIS/METHODOLOGY (VI) |
| Discussion Leader: Michael J. Luzzio (Pfizer) |
| 7:30 pm - 8:10 pm | Anthony G. M. Barrett (Imperial College)
"Recent Advances in the Total Synthesis of Antibiotic Natural Products" |
| 8:10 pm - 8:15 pm | Discussion |
| 8:15 pm -8:30 pm | Michael A. Calter (Wesleyan University)
"Asymmetric Catalysis Using Cinchona Alkaloids" |
| 8:30 pm - 8:35 pm | Discussion |
| 8:35 pm - 9:25 pm | David A. Evans (Harvard University)
"Natural Products Synthesis" |
| 9:25 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
