Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Neural Circuits and Neuromodulators in Health and Disease
Discussion Leader: Sheena Josselyn (Hospital for Sick Children / University of Toronto, Canada)
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
Kay Tye (Salk Institute for Biological Studies, United States)
"Neural Representations of Social Homeostasis"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
Kafui Dzirasa (Duke University, United States)
"Discovering and Regulating Networks for Emotion"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Brain-Wide Dynamics
Discussion Leader: Saskia de Vries (The Allen Institute for Neural Dynamics, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Karl Deisseroth (Stanford University, United States)
"Inner Workings of Channelrhodopsins and Brains"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Kanaka Rajan (Icahn School of Medicine at Mt Sinai, United States)
"Neural Network Models to Infer Adaptive and Maladaptive Brain-wide Functional Motifs"
9:55 am - 10:05 am
Discussion
10:05 am - 10:25 am
Yang Dan (University of California, Berkeley, United States)
"Sleep-Wake Dependent Global Ignition Measured with Optogenetics and Functional Ultrasound Imaging"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Gina Poe (University of California, Los Angeles, United States)
"How 10 y of Opto Studies are Resolving and Refining 100 y of Controversy in the role of Sleep for Memory"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Joshua Gordon (National Institute of Mental Health, NIH, United States)
"Optogenetic Approaches to Enhancing Oscillatory Neural Connectivity"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
He Tian (Harvard University, United States)
"All-Optical Electrophysiology Reveals Interneuron Network Dynamics In Vivo"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Maria Jose Olvera Caltzontzin (Max Planck Florida, United States) and Saskia de Vries (The Allen Institute for Neural Dynamics, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Circuits for Cognition
Discussion Leader: Conor Liston (Weill Cornell Medicine, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Sheena Josselyn (Hospital for Sick Children / University of Toronto, Canada)
"Neuronal Allocation to a Hippocampal Engram Supporting a Contextual Fear Memory"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Paul Kenny (Icahn School of Medicine at Mount Sinai, United States)
"A Septal Circuit that Links Threat-Related Contextual Information to Defensive Behaviors"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Gaby Maimon (The Rockefeller University / HHMI, United States)
"Vector Math in the Fly Brain"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Megha Sehgal (UCLA, United States)
"Co-allocation to Overlapping Dendritic Branches in the Retrosplenial Cortex Integrates Contextual Memories Across Time"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Visualizing and Manipulating Circuits
Discussion Leader: Yaniv Ziv (Weizmann Institute of Science, Israel)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Na Ji (University of California, Berkeley, United States)
"Imaging Neural Activity at High Spatiotemporal Resolution"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Daniel Aharoni (University of California, Los Angeles, United States)
"Developing New Tools for Imaging Neural Dynamics in Freely Behaving Animals"
9:55 am - 10:05 am
Discussion
10:05 am - 10:25 am
Saskia de Vries (The Allen Institute for Neural Dynamics, United States)
"Using Large Scale Physiology to Study the Functional Organization and Dynamics of the Mouse Visual Cortex"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:20 am
Andre Berndt (University of Washington, United States)
"Massively Parallel, High-Throughput Engineering of Optogenetic Biosensors for Neuronal Signaling"
11:20 am - 11:25 am
Discussion
11:25 am - 11:40 am
Jonas Wietek (Weizmann Institute of Science, Israel)
"BLAS²T: Bistable Light-Activated Silencing of Synaptic Transmission"
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
Jung Ho Hyun (DGIST, South Korea)
"Tagging Active Neurons by Soma-Targeted Cal-Light"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Zoe Christenson Wick (Icahn School of Medicine at Mount Sinai, United States)
"Closed-Loop Optogenetic Control of Single Unit Phase Locking to Endogenous Oscillations in Behaving Mice"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Circuits for Stress, Anxiety, and Fear
Discussion Leader: Natale Sciolino (University Of Connecticut, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Thomas Kash (University of North Carolina at Chapel Hill, United States)
"Probing Aversion in the Extended Amygdala"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Anna Beyeler (French Institute of Health (INSERM), France)
"Contribution of the Anterior Insular Cortex to Obesity-Induced Anxiety"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Michael Bruchas (University of Washington, United States)
"Decoding Locus Coeruleus Function in Arousal and Stress"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Kirstie Cummings (University of Alabama at Birmingham, United States)
"Control of Fear by Discrete Prefrontal GABAergic Ensembles Encoding Valence-Specific Information"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Circuits for Reward and Addiction
Discussion Leader: Steve Ramirez (Boston University, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Kate Wassum (UCLA, United States)
"Optogenetic Interrogation of Amygdala Circuits in Reward Learning and Decision Making"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
Timothy Spellman (University of Connecticut School of Medicine, United States)
"Cortical Circuits Supporting Cognitive Flexibility"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
Sandeep Robert Datta (Harvard Medical School, United States)
"Spontaneous Behavior is Structured by Reinforcement Without Explicit Reward"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
Zayd Khaliq (National Institute of Neurological Disorders and Stroke, NIH, United States)
"Membrane Potential Dynamics During Cholinergic Transmission onto Striatal Dopaminergic Axons"
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
Erin Calipari (Vanderbilt University, United States)
"Dopamine Release in the Nucleus Accumbens Signals Perceived Saliency"
11:45 am - 11:55 am
Discussion
11:55 am - 12:15 pm
Christian Luscher (University of Geneva, Switzerland)
"Optogenetic Interrogation of Addiction Circuits"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Circuits in Action
Discussion Leader: Anita Devineni (Emory University, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Mackenzie Mathis (EPFL, Switzerland)
"Deep Learning for the Analysis of Brains and Behavior"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Adam Hantman (UNC-CH, United States)
"Optogenetic Exploration of the Neural Landscapes for Skill"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
John Tuthill (University of Washington, United States)
"Proprioceptive Control of Walking in Drosophila"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Kimberly Reinhold (Harvard Medical School, United States)
"Timescale of Posterior Dorsomedial Striatum’s Contribution to Trial and Error Learning"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Circuits for Social Behaviors
Discussion Leaders: Malavika Murugan (Emory University, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Bianca Jones Marlin (Columbia University, United States)
"Sensing Trauma: the Intergenerational Inheritance of Olfactory Sensory Experience"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Dayu Lin (NYULMC, United States)
"Neural Circuit of Social Behaviors: Innate Yet Flexible"
9:55 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 10:55 am
Ishmail Abdus-Saboor (Columbia University, United States)
"A Skin-Brain Pathway for Rewarding Social Touch"
10:55 am - 11:05 am
Discussion
11:05 am - 11:25 am
Garret Stuber (University of Washington, United States)
"Medial Preoptic Area Circuits for Mating"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
Stephen Zhang (Beth Israel Deaconess Medical Center, United States)
"Dopaminergic Control of Mating Drive Over Minutes and Days"
11:50 am - 11:55 am
Discussion
11:55 am - 12:15 pm
Jessica Osterhout (University of Utah, United States)
"Molecular and Neural Control of Sickness Behavior"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Keynote Session: Biosensors for Circuits
Discussion Leader: Christina Kim (University of California, Davis, United States)
5:30 pm - 5:35 pm
Introduction by Discussion Leader
5:35 pm - 6:15 pm
Lin Tian (University of California, Davis, United States)
"Letting the Little Light of Mind Shine: Genetically Encoded Indicators for Neurochemical Detection"
6:15 pm - 6:25 pm
Discussion
6:25 pm - 6:45 pm
Michael Lin (Stanford University, United States)
"One- and Two-Photon Voltage Imaging With New ASAP-Family Indicators"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:15 pm
Luke Lavis (Janelia Research Campus, Howard Hughes Medical Institute, United States)
"Combining Chemistry and Protein Engineering to Create New Indicators for Functional Imaging"
7:15 pm - 7:25 pm
Discussion
7:25 pm - 7:30 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure