Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Vaccines, Treatment and Resistance
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:20 pm
"Mechanisms of Salmonella typhi Virulence"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"An Atlas of Human Genetic Variation Affecting Host-Pathogen Traits Reveals Regulatory Variants Modulating Salmonella Invasion and Typhoid Fever Risk"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
"Vaccines Against Nontyphoidal Salmonella: The Case, the Candidates and the Pathway Forward"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Molecular Mechanisms of Virulence
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Sweet Interaction: A Key Determinant of Typhoid Toxin's Host and Tissue Tropism"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Emerging Salmonella enterica Serovar Infantis Induces a Strong Pro-Inflammatory Response that Is Dependent on the pESI Virulence Plasmid"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Metabolite Signaling Influences Salmonella Systemic Infection"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"High-Throughput Screening of Type III Secretion Determinants"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
"When the Former Is Exploited by the Latter"
11:50 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Suppression of the Adaptive Immune Response"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Controlling Host-Membrane Trafficking to Establish Systemic Infection"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Visualization of Salmonella -Induced Filaments Through Site-Specific Fluorescent Labeling of SPI-2 SifA Effector Protein"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Colonization of the Epithelial Cell Cytosol by Salmonella "
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Interactions of Salmonella with Host Cells Through the SP1-T3SS"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Innate Immune Response
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Sensing of Salmonella by Noncanonical Inflammasomes"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Pattern Recognition Receptor Redundancy Converges on Cell Death"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Paneth Cells Secrete Lysozyme via Secretory Autophagy During Bacterial Infection of the Intestine"
10:25 am - 10:30 am
Discussion
10:30 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Innate Immune Inhibition by Salmonella Effector Proteins"
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"The Bacterial Amyloid Curli: Expression, Immune Recognition and Pathogenesis"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Intracellular Salmonella and the Second Messenger c-di-GMP"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metabolism and Pathogenesis
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Interaction of Salmonella typhimurium with the Gut Microbiota"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Microbiota-Derived Aspartate Drives Salmonella Expansion During Colitis"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:50 pm
"The Interplay of Bacterial Pathogens, Host Metabolites and Immune Factors in the Ecosystem of the Mammalian Gut"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Metabolic Adaptations to Oxidative Stress in Salmonella Pathogenesis"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Interplay Between Bacterial Genetics and Intestinal Colonization"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"RHS-Elements Function as Type II Toxin-Antitoxin Modules that Regulate Intra-Macrophage Replication of Salmonella "
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Regulation of the SPI1 Type Three Secretion System"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"The Type III Secretion Signal: Finally an Answer"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Salmonella Expresses Horizontally Acquired Genes by Degrading Their Silencer"
11:50 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Antibiotic Tolerant Salmonella During Infection"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Effective Protective Memory Responses to Salmonella Infection"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Salmonella Lipid Homeostasis for Survival and Adaptation Within Host Tissues"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Role of Inflammatory Monocytes in Salmonella Pathogenesis"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"T-Cell Specificity and the Development of Immunity in the Murine Model of Invasive Salmonellosis"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Complex Microbe-Host Interactions
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Infection of Organoids with Salmonella"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"The Host-Pathogen Interface During Salmonella Chronic Carriage"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Salmonella Single-Cell Biology During Infection: Subsets, Fates and Overall Impact on Disease Progression"
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Prepared for Every Eventuality: The Microbiota Blocks Salmonella Infection at Different Stages"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Molecular Pathogenesis of Salmonella Diarrhea"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"How Has African Salmonella Become So Dangerous?"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Salmonella Microevolution: Mechanisms and Consequences"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Endogenous Enterobacteriaceae Underlie Variation in Susceptibility to Salmonella Infection"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure