Discussion Leader: Peter Wipf - University of Pittsburgh

7:20 - 7:30 PM Welcome

7:30 - 8:30 PM Franklin Davis - Temple University
"Asymmetric Synthesis using Polyfunctionalized Chiral Building Blocks"

8:30 - 9:30 PM Gregory Fu - Massachusetts Institute of Technology
"Asymmetric Catalysis with "Planar-Chiral" Heterocycles"

9:30- 10:30 PM Reception

Discussion Leader: Denice Spero - Boehringer Ingelheim

8:30 - 9:00 AM Picture

9:00 - 9:40 AM David MacMillan - University of California, Berkeley
"Organocatalysis: A New Strategy for Enantioselective Catalysis"

9:40 - 10:20 AM Donna Blackmond - Hull University
" Kinetic Implications on Non-linear Effects in Asymmetric Catalysis"

10:20 - 10:50 AM Break

10:50 - 11:30 AM Dalibor Sames - Columbia University
"C-H Bond Activation in the Synthesis of Complex Organic Molecules"

11:30 - 12:10 PM Chris Senanayake - Sepracor
" Asymmetric Synthesis for ICEs"

12:10 - 12:30 PM Christopher Welch - Merck
"The Chirons of Titan: A Search for Extraterrestrial Enantioenrichment"

5:00 - 6:00 PM Poster Session I (1-12)

Discussion Leader: Joel Morris - Pfizer

7:30 - 8:10 PM Jeffrey Aubé - University of Kansas
"Stereoselectivity in Ring Expansion and Cyclization Reactions"

8:10 - 8:30 PM Michael VanNieuwenhze - Eli Lilly & Co.
"The First Total Synthesis of Lipid II: The Final Monomeric Intermediate in Bacterial Cell Wall Biosynthesis"

8:30 - 8:50 PM Marisa Kozlowski - University of Pennsylvania
"Identification of Novel Ligands for Asymmetric Synthesis"

8:50 - 9:50 PM Samuel Danishefsky - Columbia University/ Memorial Sloan-Kettering Institute
"Reflections on the Power of Organic Synthesis"

Discussion Leader: Edward Suh - Eisai Research Institute

8:30 - 9:10 AM John Boukouvalas - Laval University
"Recent Advances in the Asymmetric Synthesis of Natural Products of Biomedical Importance"

9:10 - 9:40 AM Daniel O'Leary - Pomona College
"NMR Methodology for Probing the Configuration of Intramolecular Hydrogen Bonds: Equilibrium Isotope Effects and Scalar Coupling Pathways"

9:40 - 10:20 AM Michel Gagné - University of North Carolina
"An Outer Sphere Approach to Controlling Catalytic Reaction Selectivities"

10:20 - 10:50 AM Break

10:50 - 11:30 AM Debra Wallace - Merck Sharp & Dohme Research Laboratories
"Diastereoselective Double Ring Closing Metathesis Reactions: Application to the Synthesis of NK-1 Receptor Antagonists"

11:30 - 12:10 AM Matthew Shair - Harvard University
"Reaction Microarrays"

12:10 - 12:30 AM Shuji Kanemasa - Kyushu University
"Lewis Acid-Catalyzed Enantioselective Conjugate Additions of Highly Coordinating Nitrogen Nucleophiles. Intramolecular Delivery as a Powerful Chirality Control Methodology"

5:00 - 6:00 PM Poster Session I (1-12 cont'd.)

Discussion Leader: Mukund Sibi - North Dakota State University

7:30 - 8:10 PM Henri Kagan - Laboratoire de Synthese Asymetrique, Université of Paris-Sud
"Asymmetric Catalysis: Asymmetric Synthesis of Some New Ligands, New Use of Some Known Ligands"

8:10 - 8:30 PM Philippe Renaud - University of Fribourg
"A Radical Alternative to the Oxy-Cope Rearrangement"

8:30 - 8:50 PM Matthias McIntosh - University of Arkansas
"Intramolecularly Competitive Ireland Claisen Rearrangements: Scope and Applications"

8:50 - 9:50 PM Masakatsu Shibasaki - University of Tokyo
"Development of Lewis Acid - Lewis Base Bifunctional Asymmetric Catalyses"

Discussion Leader: Ross Widenhoefer - Duke University

8:30 - 9:10 AM James Morken - University of North Carolina
" Development of Asymmetric Reactions Using Combinatorial Chemistry"

9:10 - 9:40 AM Debbie Crans - Colorado State University
"Chemistry and Mode of Action of Vanadium Complexes - Potential Therapeutic Agents for Type 2 Diabetes"

9:40 - 10:20 AM Laurence Nafie - Syracuse University
"Vibrational Circular Dichroism: A New Spectroscopic Tool for Determining Absolute Configuration and Conformation in Chiral Molecules"

10:20 - 10:50 AM Break

10:50 - 11:30 AM Ving Lee - Microcide Pharmaceuticals
"Uridyl Peptide Antibiotics: Serendipity, Structure, and Structure-Activity Relationships"

11:30 - 12:10 PM Takeshi Kitahara - University of Tokyo
"Studies on Stereocontrolled Synthesis of Bioactive Heterocycles - FR901464 and Kaitocephalin"

12:10 - 12:30 PM George O'Doherty - University of Minnesota
"An Enantioselective Synthesis of C-Arylglycoside Natural Products via Catalytic Dihydroxylations of Vinylfurans"

5:00 - 6:00 PM Poster Session II (13 - 21)

Discussion Leader: Daniel Sternbach - GlaxoWellcome, Inc.

7:30 - 8:10 PM Mark Rizzacasa - University of Melbourne
"Hetero-Diels-Alder Synthesis of Spiroketals: Application to the Total Synthesis of the Reveromycins and Spirofungins"

8:10 - 8:30 PM Wojciech Stec - Polish Academy of Sciences
"Oxathiaphospholane Approach to the Stereocontrolled Synthesis of P-Chiral Isotopomeric Biophosphates"

8:30 - 8:50 PM Gregory Cook - North Dakota State University
"Dynamic Diastereomers. Unusual Regioselectivity and Divergent Kinetic Resolution in the Pd-Catalyzed Allylic Substitution"

8:50 - 9:50 PM William Roush - University of Michigan
"Stereochemistry of Reactions of Complex Aldol and Allylmetal - Aldehyde Addition Reactions"

Discussion Leader: Carol Ensinger - Biogen

8:30 - 9:10 AM Craig Forsyth - University of Minnesota
"Total Synthesis of Stereochemically Complex Natural Products"

9:10 - 9:50 AM Nina Berova - Columbia University
"The Role of Circular Dichroism Spectroscopy in Solving Challenging Stereochemical Problems"

9:50 - 10:20 AM Robert Scott - Pfizer, Inc.
"A New Glycosylation Method for the Scalable Synthesis of Nucleoside Analogs"

10:20 - 10:50 AM Break

10:50 - 11:30 AM Scott Nelson - University of Pittsburgh
"New Lewis Acid Catalyst Designs Based on Highly Coordinated or Bimetallic Al(III) Complexes"

11:30 - 11:50 AM Jia-Ning Xiang - Smithkline Beecham Pharmaceuticals
"Studies and Synthesis of Structurally Constrained Biaryls as Endothelin Receptor Antagonists"

11:50 - 12:10 PM Ross Widenhoefer - Duke University
"Palladium-Catalyzed Cyclization of Functionalized Dienes"

12:10 - 12:30 PM Fraser Fleming - Duquesne University
"Unsaturated Nitriles: Stereoselective Cyclizations

5:00 - 6:00 PM Poster Session II (13 - 21 cont'd.)

Discussion Leader: Paul Lahti - University of Massachusetts

7:30 - 7:45 PM Business Meeting

7:45 - 8:30 PM Jay Siegel - University of California, San Diego
"Design of Topological Stereoisomers"

8:30 - 9:30 PM Jerome Berson - Yale University
"Stereochemical Aspects of Mechanistic Refutation, Past, Present, and Future"

9:30 - 10:30 PM Reception