SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:15 pm | Chair's Welcome and Introductory Remarks |
7:30 pm - 9:30 pm | NEW REAGENTS AND CATALYSTS |
| Discussion Leader: Karl Scheidt (Northwestwern University) |
7:30 pm - 8:20 pm | Scott Denmark (University of Illinois, Urbana-Champaign) "Asymmetric Catalysis with Main Group Chemistry: A New Frontier?" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Gregory Fu (MIT) "Coupling Reactions" |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NOVEL STRATEGIES |
| Discussion Leader: Doug Frantz (Southwestern Medical Center) |
9:00 am - 9:25 am | Karl Scheidt (Northwestern University) "Polarity Reversal Chemistry Inspired By Nature: Recent Advances Using Carbene Catalysis" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Joseph Fox (University of Delaware) "Strain as a Design Principle in Synthesis" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break / Group Photo |
10:30 am - 11:20 am | Shane Krska (Merck) "Advancing the Science and Application of Asymmetric Hydrogenation in the Pharmaceutical Industry: The Synthesis of DPP-IV Inhibitor Sitagliptin" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:20 pm | Joelle Prunet (Ecole Polytechnique, Palaiseau) "Metathesis and 1,3-Diols: Application to the Synthesis of Natural Products" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | STEREOSELECTIVE SYNTHESIS |
| Discussion leader: Joseph Fox (University of Delaware) |
7:30 pm - 8:20 pm | Shu Kobayashi (University of Tokyo) "Highly Functionalized Reaction Environments for Organic Synthesis" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Viresh Rawal (University of Chicago) "Asymmetric Catalysis of Chemical Reactions Promoted by Hydrogen Bond Activation" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am -12:30 pm | BIOLOGY AND CHEMISTRY |
| Discussion Leader: Jay Siegel (University of Zürich) |
9:00 am - 9:50 am | Sam Gellman (University of Wisconsin) "Structure and Function in Foldamers" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:25 am | Coffee Break |
10:25 am - 10:50 am | Karl Gademann (ETH-Zürich) "Synthetic Natural Products and Their Application in Chemical Biology and Materials Science" |
10:50 am - 10:55 am | Discussion |
10:55 am - 11:25 am | Ana Mapp (University of Michigan) "The Role of Stereochemistry in Transcriptional Activation" |
11:25 am - 11:35 am | Discussion |
11:35 am - 12:20 pm | Justin DuBois (Stanford University) "Stereospecific and Selective C-H Oxidation Reactions for Chemical Synthesis" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CHEMISTRY AND BIOLOGY |
| Discussion leader: Karl Gademann (ETH-Zürich) |
7:30 pm - 8:20 pm | Scott Miller (Boston College) "Stereochemical Aspects of Peptide-Based Catalysts: Sequence, Structure, Function" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Steven Benner (F. H. Westheimer Institute for Science and Technology) "Synthesis, Chirality, and Darwinian Chemistry" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am -12:30 pm | NOVEL METHODOLOGY |
| Discussion Leader: Rene Peters (ETH Zürich) |
9:00 am - 9:50 am | Jim Edwards (Johnson & Johnson) "New Noncovalent Inhibitors of Cathepsin S" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:25 am | Coffee break |
10:25 am - 10:55 am | Hélène Lebel (Université de Montréal) "Catalytic Activation of Nitrogen Derivatives with Transition-Metal Complexes" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:50 am | John Hartwig (Yale University) "Enantioselective Iridium-Catalyzed Allylic Substitution" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session A |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | METHODOLOGY |
| Discussion leader: Hélène Lebel (Université de Montréal) |
7:30 pm - 8:20 pm | Andrei Yudin (University of Toronto) "Strained Enamines in Synthesis" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | André Charette (Université de Montréal) "Catalytic Asymmetric Reactions with Diorganozinc Reagents" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am -12:30 pm | CATALYSIS |
| Discussion Leader: Andrei Yudin (University of Toronto) |
9:00 am - 9:50 am | Janine Cossy (ESPCI, Paris) "Stereoselective Metalations and Metathesis Reactions Synthesis of Biologically Active Compounds" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:20 am | Jade Nelson (Pfizer) "Large-Scale Asymmetric Synthesis of Chiral 1,3-Syn-Diols: An Alternate Process for Atorvastatin Lactone Production" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:20 pm | Vittorio Farina (Boeringer Ingelheim) "Synthesis of New HCV Protease Inhibitors by a Convergent Synthesis Featuring Ring-closing Metathesis" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session B |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | SYNTHESIS |
| Discussion leader: Joelle Prunet (Ecole Polytechnique, Palaiseau) |
7:30 pm - 7:55 pm | Alison Frontier (University of Rochester) "Recent Developments in Nazarov Cyclization Chemistry" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm-8:25 pm | Rene Peters (ETH- Zürich) "Development of Practical Catalytic Asymmetric Methodologies for Rapid Access to High-Added-Value Building Blocks" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | David Evans (Harvard University) "Recent Advances in Complex Molecule Synthesis" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |