SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:35 pm | Welcome / Introductory Comments by GRC Site Staff |
7:35 pm - 9:30 pm | Stereochemical Biology |
| Discussion Leader: Chris Seto (Brown) |
7:35 pm - 8:05 pm | Virginia Cornish (Columbia) "The Ribosome Discriminates the Structure of the Amino Acid at It's Peptidyltransferase Center" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:45 pm | Sarah O'Connor (MIT) "Stereochemistry in Indole Alkaloid Biosynthesis" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:25 pm | Carole Bewley (NIH) |
9:25 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stereoselective Synthesis |
| Discussion Leader: Seth Herzon (Yale) |
9:00 am - 9:35 am | Phil Baran (TSRI) "Aiming for the Ideal Synthesis" |
9:35 am - 9:40 am | Discussion |
9:45 am - 10:20 am | Shenming Ma (SIOC) "Stereoselective Synthesis based on the Chemistry of Allenes" |
10:20 am - 10:25 am | Discussion |
10:30 am | Group Photo / Coffee Break |
11:00 am - 11:35 am | Matt Sigman (Utah) "New Approaches to the de novo Design of Asymmetric Catalysts" |
11:35 am - 11:40 am | Discussion |
11:45 am - 12:20 pm | Erik Sorensen (Princeton) "Strategic applications of double cyclizations in complex natural product synthesis" |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Materials Stereochemistry |
| Discussion Leader: James Canary (NYU) |
7:30 pm - 8:05 pm | Patrick Vaccaro (Yale) "Absolute Stereochemical Configuration and Optical Activity: New Twists on an Old Topic" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:45 pm | Geoff Coates (Cornell) "New Catalysts for Stereoselective Polymerization" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:25 pm | Kyoko Nozaki (Tokyo) "Structural Control in Polymerization Utilizing CO or CO2" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stereoselective Catalysis I |
| Discussion Leader: Abigail Doyle (Princeton) |
9:00 am - 9:35 am | Magnus Rueping (RWTH Aachen) "Asymmetric Brønsted Acid Catalysis - Concepts and Applications" |
9:35 am - 9:40 am | Discussion |
9:45 am - 10:20 am | Dan Yang (Hong Kong) "Stereoselective Cyclization Reactions through Palladium and Silver Catalysis" |
10:20 am - 10:25 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:35 am | Tobias Ritter (Harvard) "Late-Stage Fluorination" |
11:35 am - 11:40 am | Discussion |
11:45 am - 12:20 pm | Tom Lectka (Johns Hopkins) "Asymmetric alpha-Fluorination Leading to Serendipitous Discoveries" |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Resolution |
| Discussion Leader: Kurt Mislow (Princeton) |
7:30 pm - 8:05 pm | Chris Welch (Merck) "Recent Studies on the Analysis and Purification of Stereoisomers Using Chromatography" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:45 pm | Bernhard Kaptein (DSM) "Attrition enhanced deracemization under solid-liquid near-equilibrium conditions" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:25 pm | Michael McBride (Yale) "Grinding to Homochirality - The Mechanism of Viedma Ripening" |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stereoselectivity on Scale |
| Discussion Leader: Vittorio Farina (Johnson and Johnson Pharmaceutical R&D) |
9:00 am - 9:35 am | Joel Hawkins (Pfizer) "Enantio- and Diastereoselective Hydrogenations of Pharmaceutical Intermediates" |
9:35 am - 9:40 am | Discussion |
9:45 am - 10:20 am | Jean-Michel Adam (Roche) "Process Research towards a Scalable Route for a Roche Factor Xa Inhibitor" |
10:20 am - 10:25 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:35 am | Klaus Ditrich (BASF) "ChiPros® - Optically Active Intermediates on an Industrial Scale" |
11:35 am - 11:40 am | Discussion |
11:45 am - 12:20 pm | Chris Senanayake (Boehringer Ingelheim Pharmaceuticals, Inc) "Asymmetric Synthetic Methodologies for Efficient Drug Development" |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Medicinal Stereochemistry |
| Discussion Leader: Sarah Reisman (Caltech) |
7:30 pm - 8:05 pm | Frank Fang (Eisai) "Process Research on Natural Product Based Drug Candidates" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:45 pm | Sheng Cui (Amgen) "Development of a Practical Enantioselective Conjugate Alkynylation" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:25 pm | Jonathan Elman (UC Berkeley) "The Asymmetric Synthesis of Amines" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stereoselective Catalysis II |
| Discussion Leader: Vy Maria Dong (Toronto) |
9:00 am - 9:35 am | Michael Krische (UT Austin) "Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation" |
9:35 am - 9:40 am | Discussion |
9:45 am - 10:20 am | Marisa Kozlowski (Penn) "Asymmetric Oxidative Coupling and Claisen Rearrangements" |
10:20 am - 10:25 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:35 am | Helma Wennemers (Basel) "Bioinspired Asymmetric Catalysis" |
11:35 am - 11:40 am | Discussion |
11:45 am - 12:20 pm | Amir Hoveyda (Boston College) "Learning from Nature through Catalyst Development" |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Supramolecular Stereochemistry |
| Discussion Leader: Michael Martinelli (Arena) |
7:30 pm - 8:05 pm | David Sherman (Michigan) "Structural Diversity and Enzymatic Versatility in Natural Product Biosynthesis" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:45 pm | Makoto Fujita (Tokyo) "Nanoscale Coordination Architectures: Self-Assembled Molecular Spheres" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:25 pm | Ned Seeman (NYU) "DNA: Not Merely the Secret of Life" |
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |