Molecular Recognition: A. Schwabacher, discussion leader
W. Jorgensen, "Insights on Molecular Recognition in Organic and
Biochemical Systems from Computer Simulations."
D. Reinhoudt, "A Comparison of Synthetic and Natural Receptors."
H-J. Schneider, "Mechanisms of Molecular Recognition and
Supramolecular Catalysis."
Artificial Enzymes and Catalysts: J. Chmielewski, discussion leader
S. Benner, "Designing Peptide Catalysts: The Role of Detailed Kinetic
Analysis."
E. Jacobsen, "Synthetic and Biological Catalysts for Enantioselective
Oxidations of Hydrocarbons."
C. Wilcox, "Intermolecular Forces and Synthetic Enzymes."
Nucleic Acids: A. Schepartz, discussion leader
J. Barton, "Probing Nucleic Acids with Transition Metal Complexes: Is
the DNA Helix a Wire?"
G. Glick, "Engineering Disulfide Bonds into Nucleic Acids."
D. Herschlag, "Mechanisms of Catalysis by RNA Enzymes."
J. Williamson, "Molecular Recognition: How RNAs See Proteins."
Chemical Diversity: E. Gordon, discussion leader
M. Gallop, "Applications of Encoded Synthetic Libraries to Drug
Discovery."
W. C. Still, "Using Encoded Combinatorial Synthesis to Solve Problems
in Molecular Recognition."
J. Szostak, "Selection of New Ribozymes from Large Pools of Random
Sequences."
Enzymes and Enzyme Complexes: D. Trainor, discussion leader
J. H. Griffin, "Structure/Function and Inhibitor Analysis of Yeast
Oxidosqualene Cyclase Enzymes."
C. R. Hutchinson, "How to Make Bacteria do it Differently: Construction
of Novel Natural Products by the Genetic Engineering of
Microorganisms."
R. Parry, "Recent Investigations of Antibiotic Biosynthesis."
G. Prestwich, "Dangerous Liaisons: Active Site Affinity Labels for
Vertebrate Squalene Epoxidase and Oxidosqualene Cyclase."
Medicinal Chemistry/Molecular Design: E. Petrill, discussion leader
S. Bender, "Functional Consequences of the Catalytic Site Structure of
Matrix Metalloproteinases."
L. Griffin, "Aptamer Technology: Discovery and Development of a
Novel Nucleotide-Based Thrombin Inhibitor."
W. Lau, "Structure-Based Design of Novel Thrombin Inhibitors."
Signal Transduction: T. von Geldren, discussion leader
P. Kim, "Coiled Coils: Natural, Designed and Spring-Loaded."
E. Laird, "Computational Exploration of Peptide Binding to SH2
Domains."
J. Marsters, "Inhibitors of Ras Farnesyltransferase."
Mechanisms of Resistance
S. Hughes, "Structural and Biochemical Analysis of HIV-1 RT Drug
Resistance."
C. Walsh, "Enzymes in Bacterial Cell Wall Biosynthesis."
Receptors
D. Koshland, "Response Regulators in Procaryotes and Eucaryotes."
J. Wells, "Designing Growth Hormone Receptor Interactions."
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